The structural frame is designed to continuously withstand the vertical gravitational loads (self-weight, masonry walls, floor coverings, cars, furniture, people etc) and, not in a continuous but in a periodical basis, the wind and snow actions. Moreover it must always bear the “self-induced” loadings caused by temperature changes etc.
Apart from the usual loads, in earthquake prone regions, the structural frame must have enough strength surplus distributed in such a way so that in the critical moment of an earthquake, to be able to respond successfully, retaining the building intact.